viernes, 28 de noviembre de 2008

Cethromycin Achieves All Endpoints In Second Pivotal Phase III Trial For Treatment For Pneumonia Part 3




Since p>0.05, at hand be not a statistically carrying great mass distinction by the tenderloin of the topic of cethromycin and Biaxin, which supports non-inferiority.



Further enquiries to: Media Enquiries: Edel McCaffrey, Tel: +44 (0) 207 304 5034 Steve Brown, Tel: +44 (0) 207 304 5033 Investor Relations: Mina Blair Robinson, Tel: +44 (0) 207 304 5084 Jonathan Hunt, Tel: +44 (0) 207 304 5087 Notes to editors: AstraZeneca is a through an assortment of healthcare business affianced in the research, growth, fabrication and marketing of prescription pharmaceuticals and the provide of healthcare services. It is one of the world's prime pharmaceutical company with healthcare sales of concluded $18.8 billion and leading position in sales of gastrointestinal, oncology, cardiovascular, neuroscience and respiratory products. AstraZeneca is timetabled in the Dow Jones Sustainability Index (Global and European) above and gone in lay of the FTSE4Good Index. Nexium® is a trademark of the AstraZeneca cloud of companies.



* Per protocol radiographic glory rate- cethromycin 92.7% (202 subjects/218 subjects) compared to Biaxin 92.3% (192 subjects/208 subjects) [-4.9, +5.6] (p>0.9999). Based on the 92.7% radiographic success rate for cethromycin being greater than 90%, a delta value of 10% or less on the lower bound and greater than zero on the upper bound [-4.9, +5.6] establishes non-inferiority. Under this analysis, the study met the radiographic success rate endpoint in the PPc population. Since p>0.05, there is not a statistically significant difference between cethromycin and Biaxin, which supports non-inferiority.




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